T-cell receptor - definição. O que é T-cell receptor. Significado, conceito
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O que (quem) é T-cell receptor - definição


T-cell receptor         
  • Antigen presentation stimulates T cells to become either "cytotoxic" CD8+ cells or "helper" CD4+ cells.
MOLECULE FOUND ON THE SURFACE OF SOME IMMUNE CELLS
Alpha-beta T-cell antigen receptor; Genes, t-cell receptor; T-cell receptors; Receptors, antigen, t-cell; T-cell antigen receptors; TCRδ1; TCRd1; T cell receptor
The T-cell receptor (TCR) is a protein complex found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen as peptides bound to major histocompatibility complex (MHC) molecules. The binding between TCR and antigen peptides is of relatively low affinity and is degenerate: that is, many TCRs recognize the same antigen peptide and many antigen peptides are recognized by the same TCR.
T cell receptor T cell therapy         
T cell receptor T cell therapy (TCR-T) is a type of cancer immunotherapy. TCR-T therapies use heterodimers made of alpha and beta peptide chains to recognize MHC-presented polypeptide fragments molecules.
Chimeric antigen receptor T cell         
  • Depiction of adoptive cell transfer therapy with CAR-engineered T cells
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  • Different components of a chimeric antigen receptor
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  •  doi = 10.7150/jca.2.378 }}</ref>
ARTIFICIAL T-CELL RECEPTOR FOR USE IN IMMUNOTHERAPY
Chimeric T cell receptor; Artificial T cell receptors; Artificial t cell receptor; Artificial T cell receptor; Chimeric Antigen Receptor; CAR-T; Genetically engineered T cell; Engineered T-cell; Chimeric antibody receptor; CAR-T therapy; CAR T-cell therapy; CAR-T cell; CAR T cells; Chimeric antigen receptor; CAR-T Cell Therapy; CAR-T cells; Chimeric antigen receptor T cell; CAR T-cell
Chimeric antigen receptor T cells (also known as CAR T cells) are T cells that have been genetically engineered to produce an artificial T cell receptor for use in immunotherapy.